Onondaga County, NY

Businesses For Sale in Onondaga County, NY

Showing 59 results sorted by
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Profitable Ground Transport Company Serving Medical & Community Client

Onondaga County, NY

A well-run regional passenger transportation company operating across multiple counties in upstate New York is now available for acquisition. The business holds a stable position in a market with...

$745,000

Cash Flow: $215,000

$745,000

Cash Flow: $215,000

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Established FedEx Linehaul | 8 Dedicated Runs | Fleet Included

Syracuse, NY

Established in 2002, this is a long-standing FedEx Linehaul operation offering immediate scale across the Syracuse and Binghamton, New York dispatch locations. The portfolio consists of eight...

$2,995,000

Cash Flow: $993,723

$2,995,000

Cash Flow: $993,723

Exclusive Territory Medical Device Distribution Business -High Margins

Onondaga County, NY

This is a rare opportunity to acquire a highly profitable, relationship-driven business operating within a specialized segment of the healthcare supply chain. The Company serves an established base of...

$9,499,999

Cash Flow: $1,564,211

$9,499,999

Cash Flow: $1,564,211

New Preschool/Daycare with #1 Franchise - Clay, NY
Asset Sale

Clay, NY

The Learning Experience is a recognized leader in the daycare and early education industry with over 430+ centers open and another 250+ under development. This is your opportunity to be part of an...

$150,000

14

$150,000

Central NY Industrial Value-Add Opportunity

Auction by Ten-X™

Syracuse, NY

Online auction: September 14-16, 2026

47,132 SF Manufacturing For Sale...

Not Disclosed

39
Starting bid:

Not Disclosed

REAL ESTATE INCLUDED

Successful Bakery For Sale

Syracuse, NY

Incredible opportunity to acquire Honeycomb Bakery, one of Central New York’s most highly regarded independent bakeries. Established in 2020, this family-owned business specializes in high-quality,...

6

$159,900

$159,900

Cash Flow: $100,000

17 Year Established, Open and Operating Home Services Franchise Resale

Onondaga County, NY

This is an established, open, and operating franchise resale opportunity. We sell and install through well-equipped mobile showrooms. As the largest provider of custom products in North America, we...

$280,000

$280,000

Profitable Dessert Franchise with Management in Place

Onondaga County, NY

Established national dessert franchise located in the greater Syracuse, NY market. The business generated approximately $1.15 million in trailing twelve-month revenue and approximately $210,000 in...

$590,000

$590,000

Cash Flow: $210,442

Japanese Ramen restaurant for Sale

Syracuse, NY

Established Japanese ramen & poke bowl restaurant for sales, all equipment stay. Great potential growth in revenue....

6

$70,000

$70,000

One of the Skaneateles's Best Loved French Bistros

Skaneateles, NY

A Rare Opportunity: Charming Restaurant & Estate for Sale Discover a truly special offering — a turnkey restaurant property that blends French country elegance with untapped potential. Set on over...

2

$895,000

$895,000

iSmash
Franchise

Available Nationwide

New Immersive Attractions, Low Start-Up, Avg. $232k Net Profit*, join the fastest growing entertainment brand with 100+ units sold

$100,000

$100,000

Avg. Unit Revenue: $705,011

One of CNY's longest established Nail Salons is now for sale

Onondaga County, NY

Exceptional opportunity to acquire one of Central New York's longest-established nail salons, operating continuously for 30 years since 1995. This profitable business generates $630,000 in annual...

$214,500

$214,500

10+ Unit Base – Recognized Concept + Corporate Support – Syracuse

Syracuse, NY

Confidential acquisition opportunity — multi-unit food platform, 11 locations in Syracuse NY area. A cash-flowing operating base under a recognized national concept is available to qualified,...

$1,650,000

$1,650,000

Recycling Circuit Board Depopulator For Sale

Baldwinsville, NY

We are selling the first floor model production unit (shown in attached photos), in addition to the 3D CAD drawings, website, specifications to build and sell a circuit board depopulator. The...

6

$225,000

$225,000

Turnkey fast-casual pizza restaurant available in Central New York

Onondaga County, NY

Established fast-casual pizza franchise location available in Central New York. Fully built-out restaurant operating in a high-traffic retail area with established customer base and experienced staff...

$189,000

$189,000

Updated Asking Price - Turnkey Donut Coffee Shop

Onondaga County, NY

Profitable Donut & Coffee Shop for Sale – Turnkey Business Established donut and coffee shop for sale in a prime, high-traffic location in Syracuse, NY. This is a fully operational, turnkey business...

$109,000

$109,000

Cash Flow: $400,000

Jonathan Nappa

First Choice Business Brokers of Manhattan

Serving Onondaga County, NY

Founded in 1994, First Choice Business Brokers is one of the largest Business Sales Organizations in the world, with multiple offices located throughout the U.S. listing over $7 billion worth of businesses. Our New York City office consists of 1 Principal, 3 Associates, and administrative personnel. In addition, we have a select team of professional service providers we can recommend that can provide legal, accounting, planning, financing and various other services. First Choice Business Brokers is a member in good standing with the Better Business Bureau (A+ Rating). The FCBB office is located in Manhattan which covers the entire New York and New Jersey Regions. The Principle Broker, Gregory J. Carafello, has over 38 years of extensive Business Ownership experience as a small to medium sized business owner since 1998.

Contact Me >

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$2M+ Revenue Turnkey Waterfront Restaurant & Real Estate

REAL ESTATE INCLUDED

Onondaga County, NY

Confidential opportunity to acquire a fully renovated, high-volume waterfront restaurant and hospitality operation with historical revenues averaging approximately $2.3 million annually since opening...

$1,550,000

$1,550,000

Cash Flow: $350,000

REAL ESTATE INCLUDED

Turn Key Auto Repair Facility with Upside

REAL ESTATE INCLUDED

East Syracuse, NY

Established Auto Repair Facility with Income-Producing Property This turnkey auto repair business presents a unique investment opportunity combining a profitable service operation with real estate...

$425,000

$425,000

Cash Flow: $512,811

REAL ESTATE INCLUDED

E-Commerce Women's Clothing Store - huge price drop Nov 2025

Onondaga County, NY

Turnkey E-Commerce Retail Store for Sale – Your Gateway to Online Success! This fully operational e-commerce retail store is now available for sale, offering you a streamlined, profitable, and...

$40,000

$40,000

Cash Flow: $28,000

Growing profitable Diner in the Village with 30% growth YOY

REAL ESTATE INCLUDED

Onondaga County, NY

A well-established 20 year old diner in the a growing Syracuse suburb. Operating from 6/7 am to 1pm, Tuesday to Sunday, it offers a timeless menu with a wide range of options. Customers, 80% which are...

$350,000

$350,000

Cash Flow: $150,000

REAL ESTATE INCLUDED

Established Physical Therapy Office with Staff

Onondaga County, NY

Overview: This is a unique opportunity to acquire a well-established physical therapy office with a strong reputation, established professional staff and consistent client base. Located in centralized...

$215,000

$215,000

Cash Flow: $122,000

Dumpster Dudez
Franchise

Available in New York

Dumpster Dudez - Choose Orange. Choose the Best. Choose Dumpster Dudez!

$200,000

$200,000

Avg. Unit Revenue: $411,683

Profitable Commercial Cleaning with long term clients

Onondaga County, NY

Family owned and operated team of proud professionals with decades of experience. Business able to handle most janitorial needs offering office and commercial cleaning for 38+ years. Janitorial,...

$550,000

$550,000

Cash Flow: $162,000

Profitable Fitness Studio in growing CNY suburb

Onondaga County, NY

Step into ownership of an established, fully-equipped fitness studio with a loyal client base and strong local reputation. Located in a high-traffic area of CNY, this modern facility offers everything...

$225,000

$225,000

Cash Flow: $120,000

Interpretation Service Business in CNY - needs new leader!

Onondaga County, NY

Well-established CNY business providing interpretation of spoken language in 10 different languages, specialty in Spanish, Ukrainian, Arabic, Spanish, Russian, Polish, and Chinese. Eleven year track...

$350,000

$350,000

Cash Flow: $172,810

Price Drop! Established Dry Cleaner with Plant - Syracuse, NY

REAL ESTATE INCLUDED

Onondaga County, NY

This is a well-established dry cleaning business with good cash flow, a loyal customer base, and consistent recurring revenue. Located on on a high traffic road. This is the only dry cleaner in town...

$700,000

$700,000

Cash Flow: $170,000

REAL ESTATE INCLUDED

Project Silvered Leviathan

REAL ESTATE INCLUDED

Jordan, NY

Project Silvered Leviathan is a well-established waste and bulk materials transportation company operating across multiple regions in the Northeastern United States, including New York, Massachusetts,...

$15,000,000

$15,000,000

Cash Flow: $2,678,912

REAL ESTATE INCLUDED

Entry Level Well Connected Construction Company

Onondaga County, NY

This is a business not often seen nor thought of. There's "riches in niches" absolutely applies to this business. It is a business which serves as the initiating signal of any upcoming commercial...

$149,000

$149,000

Cash Flow: $55,000

Established Family-Owned Restaurant – Onondaga County, NY

Onondaga County, NY

Asking price: $125,000 · Gross revenue: $588,000 · Cash flow (SDE): $25,000 · FF&E included: $75,000 Priced Below Replacement Cost – Owner Retiring Well-established, family-owned and operated...

$125,000

$125,000

Cash Flow: $15,072

Established Tax & Accounting Practice — Syracuse Area

Onondaga County, NY

Business Overview Long-established CPA practice serving individuals and small businesses throughout Central New York. Decades of continuous operation have produced a deep, loyal client base that...

$880,000

$880,000

Cash Flow: $193,300

Scalable Exercise Equipment Repair Business

Syracuse, NY

Anyone looking to acquire a scalable exercise equipment repair business should consider this focused service opportunity. The company provides maintenance and repair for commercial and home exercise...

$247,999

$247,999

Cash Flow: $127,661

Established Pizzeria, Subs, Wings & Event Space

Syracuse, NY

AMD Custom Business Brokers is pleased to present an opportunity to own a well-established and profitable pizzeria that has been serving its community since 1994. The pizzeria occupies approximately...

$150,000

$150,000

Cash Flow: $56,822

Pacific Lawn Sprinklers
Franchise

Available in New York

The leading name in IRRIGATION

$100,000

$100,000

Avg. Unit Revenue: $1,125,789

19 FedEx Ground Routes - Syracuse, NY - Seller & Vehicle Financing

Syracuse, NY

The Asking Price for all routes, including 19 vehicles, is $850,000 in outright cash, plus $75,000 in estimated possible vehicle financing, plus $75,000 in seller financing (Total Purchase Price:...

$1,000,000

$1,000,000

Cash Flow: $319,341

SBA! 8 FedEx Solo Runs, 7 Dedicated, with Manager, 8+ years

Syracuse, NY

Rare opportunity to acquire a well-established FedEx Linehaul operation with a strong track record and consistent growth. Seller-owned and operated for over 8 years. Full tax return data available...

$2,599,500

$2,599,500

Cash Flow: $532,481

Looking for an opportunity? Storage and Moving Company

Syracuse, NY

JUST LISTED!! (Summer 2026) Located in Rochester ! TURNKEY OPERATION Well-run! Well-staffed (roster of ten or twelve active movers and staff)! Well-running equipment and vehicles (five moving trucks)!...

$575,000

$575,000

Cash Flow: $200,000

SG 11724 New York Syracuse South Branded Gas Station C Store Fast Food

REAL ESTATE INCLUDED

Onondaga County, NY

$3,800,000 PLUS INVENTORY for the New York Syracuse South Branded Gas Station C Store Fast Food business and property. $175,000 average inside merchandise Sales with higher margins of profits, which...

$3,800,000

$3,800,000

Cash Flow: $1,000,000

REAL ESTATE INCLUDED

Clothing Business in Onondaga - 80724

Onondaga County, NY

Excellent opportunity to acquire a well-established clothing retail business with a strong brand presence and loyal customer base. Attractive retail location providing a strong foundation for future...

$275,000

$275,000

Cash Flow: $75,000

HOODZ
Franchise

Available Nationwide

Own a Commercial Kitchen Hood Cleaning Business That Keeps the Food Service Industry Running

$100,000

$100,000

Avg. Unit Revenue: $575,405

Clothing Business in Syracuse - 80723

Onondaga County, NY

Excellent opportunity to acquire a well-established clothing retail business with a strong brand presence and loyal customer base. Attractive retail location providing a strong foundation for future...

$225,000

$225,000

Cash Flow: $55,000

Clothing Business in Onondaga County - 80714

Onondaga County, NY

Excellent opportunity to acquire a well-established clothing retail business with a strong brand presence and loyal customer base. Attractive retail location providing a strong foundation for future...

$175,000

$175,000

Cash Flow: $58,000

30+ Years of Profitable Specialty Equipment Distribution

Onondaga County, NY

This established equipment distribution company represents a premier investment opportunity in the specialty restaurant equipment sector, having operated profitably for over 30 years with exclusive...

$750,000

$750,000

Cash Flow: $228,000

Established Auction & Liquidation Business

Onondaga County, NY

This is your opportunity to acquire a well-established auction and asset liquidation company with over 53 years of continuous operation. This business operates on a proven, commission driven model...

$499,000

$499,000

Cash Flow: $220,000

Top-Performing Franchise Fitness Location For Sale

Onondaga County, NY

HS Listing ID-71251 High-Performing, Cash-Flowing Franchise | Absentee-Owned | Turnkey 180k in assets and 40k Franchise Territory included Investment Overview Opportunity to acquire a top-performing...

$139,000

$139,000

Cash Flow: $72,000

Mark Travis

Skylight Intermediaries, LLC.

Serving Onondaga County, NY

Skylight Intermediaries is a Lower Middle Market Merger & Acquisitions Advisory company. We also have a Business Brokerage division with exceptional expertise in restaurant consulting and business exit. Utilizing three brokers and an administrative staff, we cover all of NY state, Pennsylvania and Ohio. We employ the newest methods of buyer acquisition along with old fashion, in-person hand holding through the entire sale process. From pre-qualification and business prep, all the way to the closing table and beyond, we give your business the attention it deserves at a competitive rate. Offices in Syracuse and Buffalo. Coming soon to Rochester.

Contact Me >

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Turnkey Office Furniture Installation – Profitable and Scalable

Onondaga County, NY

This profitable office furniture installation company is a trusted partner for businesses upgrading, expanding, or relocating their workspaces. With a skilled crew, efficient processes, and a...

$437,000

$437,000

Cash Flow: $200,000

44 Year Established Syracuse Convenient Store with Property

REAL ESTATE INCLUDED

Onondaga County, NY

HS Listing ID-70979 Asking Price: $2,199,000 Gross Revenue: $2,150,000 Cash Flow (SDE): $537,000+ Monthly Cash Flow: ~$44,792 Property: 0.47 Acre Commercial Parcel (Included) Location: Syracuse, NY...

$2,199,000

$2,199,000

Cash Flow: $537,000

REAL ESTATE INCLUDED

Syracuse Gas Station with C Store And Property

REAL ESTATE INCLUDED

Syracuse, NY

HS Listing ID-70920 Syracuse Gas Station – Prime Corner Location + 1 Acre | High-Income Asset Asking Price: $2,900,000 Cash Flow / Income: $204,000+ (Annualized) Property: Standalone Corner Lot –...

$2,900,000

$2,900,000

REAL ESTATE INCLUDED

Turnkey Medical Transportation Business with 50 vehicles

Syracuse, NY

Introducing an incredible opportunity in Syracuse, NY! EMPIRE DM offers a thriving 30+ VEHICLE MEDICAL TRANSPORTATION BUSINESS for sale. Boasting over 60 vehicles, 30 of them DOT compliant vehicles,...

$1,500,000

$1,500,000

High-Profit Restaurant Group | Semi-Absentee Multi-Unit Brand

Onondaga County, NY

An extraordinary opportunity to acquire a premier, management-run hospitality group in the Greater Syracuse area. Generating over $1 M in Seller’s Discretionary Earnings (SDE), this two-location...

Not Disclosed

Not Disclosed

Cash Flow: $1,325,739

Black Optix Tint
Franchise

Available Nationwide

Black Optix Tint is a premium window tint and auto styling franchise built for owners who want a polished, modern operation backed by United Franchise Group. We focus on auto tint, paint protection film (PPF), ceramic coatings, and residential/commercial tint, delivering clean installs, an upscale showroom experience, and five-star customer care.

$60,000

$60,000

Turn Key High-End Nail Salon [15 yrs], Syracuse, NY 13206

Syracuse, NY

Turnkey salon opportunity in Syracuse, NY 13206—priced at $129,300. This retail store with 1,750 sf on the ground, is fully equipped with nail tables, pedicure chairs, etc, located at one of the...

$129,300

$129,300

Cash Flow: $128,000

Ambulette/Transport/Courier Company for Sale

Onondaga County, NY

LISTING ID # 36711 This long-established (16 years), family-run non-emergency medical transport (NEMT) company is licensed in 12 Central New York counties and holds a unique MLT DOT Top Vendor status,...

$1,700,000

$1,700,000

Cash Flow: $545,891

Growing Commercial Lawn Care & Snow Maintenance Business – CNY

Onondaga County, NY

A rare opportunity to acquire a thriving, year?round service company with strong recurring revenue and long?term commercial contracts. Located in the heart of Central New York, this well?established...

$550,000

$550,000

Cash Flow: $253,747

Established 55-Year Commercial Electrical Contractor in CNY

Onondaga County, NY

Rare opportunity to acquire a highly profitable, long-standing commercial electrical contractor with an exceptional reputation and deep roots in the community. For over 55 years, this company has...

$2,425,000

$2,425,000

Cash Flow: $634,000

Strong Recycling and Junk Hauling Business with Growing Revenue

Onondaga County, NY

20+ years of cleanouts and junk hauling with on call pickups and on-site trailers, along with scrap tire removal and waste tire recycling, serving a long-term and diverse customer base....

$295,000

$295,000

Cash Flow: $77,979

Taste Buds Kitchen
Franchise

Available in New York

Taste Buds Kitchen is a unique culinary experience—kids’ kitchen by day, adult BYOB kitchen by night. We deliver fun, hands-on cooking classes, camps, parties, and corporate events in stylish, upscale kitchens designed to impress guests ages 2 to 99. More than just a cooking class, Taste Buds Kitchen creates memorable, joy-filled experiences that bring people together around food. Behind the scenes, franchise owners benefit from exceptional training, proven systems, and a clear, streamlined path to success led by an experienced leadership team. This is an emerging, in-demand franchise that blends entertainment, education, and community—turning the kitchen into a place where confidence grows, connections are made, and memories last long after the aprons come off.

$150,000

$150,000

Avg. Unit Revenue: $701,223

Established Fine Dining Restaurant in Popular Neighborhood

Onondaga County, NY

Our fine dining restaurant delivers an elevated culinary experience with refined cuisine, exceptional service, and an elegant atmosphere. Featuring seasonal ingredients, a curated wine list, and...

$550,000

$550,000

Cash Flow: $350,000